As members of the ARC Centre for Excellence in Biotechnology and Development, we have begun to examine the specification and differentiation of the male germ line. This collaborative group aims to dissect the complex developmental networks underlying germ cell differentiation, with the aims of identifying genes involved in testicular and childhood cancers, elucidating mechanisms underlying idiopathic male infertility, developing new approaches to transgenic animal production, identification new targets for pest control, reprogramming germ cells for applications in biotechnology, and formulating strategies for enhancing or suppressing fertility.

Key Technologies

Microarray screening, gene expression studies, derivation of stem cell populations, in-vitro differentiation of ES cells, transgenic mouse production, gene knockout studies.

Key publications