<b>Professor Rob Capon</b><br>
Postgraduate Coordinator <br>
Group Leader, Chemistry and Structural Biology Division<br>
Investigator, Centre for Pain Research<p>
P: +61 7 3346 2979<br>
E: r.capon@imb.uq.edu.au<p>
<b>Keywords</b><br>
- Alzheimer's disease<br>
- Parkinson's disease<br>
- cancer<br>
- infectious disease<br>
- malaria<br>
- tuberculosis<br>
- bacterial/fungal/parasitic infections<br>
- pain<br>
- obesity
Professor Rob Capon
Postgraduate Coordinator
Group Leader, Chemistry and Structural Biology Division
Investigator, Centre for Pain Research

P: +61 7 3346 2979
E: r.capon@imb.uq.edu.au

Keywords
- Alzheimer's disease
- Parkinson's disease
- cancer
- infectious disease
- malaria
- tuberculosis
- bacterial/fungal/parasitic infections
- pain
- obesity

Visit the Capon Lab website for more information.

Molecular Biodiscovery: learning from nature

Natural products are a hidden and almost limitless molecular resource that, with the right combination of expertise and technology, can be found in animals, plants and microbes. Modern societies have come to rely heavily on natural products, for example, as pharmaceuticals to treat infection, cancer, pain and other illnesses; and as agricultural chemicals to control disease and improve productivity in crops and livestock.

Our research is leading the discovery of Australian natural products, and is one of only a few laboratories in the world specialising in marine and microbial biodiversity. The knowledge that we discover informs our understanding of the role of chemicals in nature, and inspires the development of valuable new pharmaceuticals, agrochemicals and more.

Together, with a network of academic and industry collaborators, we are exploring the application of new natural products to treat an array of human diseases, including tuberculosis, malaria, Alzheimer’s, cancer, pain and obesity; as well as agrochemical challenges, including parasitic infections in sheep, goats, and cows. We are also applying our skills to better understand the chemical ecology of the cane toad, to develop a means to control this invasive pest that is poisoning many of Australia’s native predator species, including quolls, lizards, snakes and crocodiles.

During 2013, we patented a new environmentally sustainable cane toad control solution utilising natural toad pheromones, and a new class of anthelmintic effective against multidrug-resistant gastrointestinal nematode infections in sheep. Both discoveries have attracted significant industry interest, and we hope to progress these opportunities in the near future. We are also working on developing natural product-inspired treatments for pancreatic cancer, chronic inflammatory pain, tuberculosis and malaria. 

Make a difference to Professor Capon's research by donating today. 

Research training opportunities

Please visit IMB's postgraduate website for full details.

Key publications

View more publications by Professor Capon via Pubmed or via UQ Researchers

Salim A.A., Xiao X., Cho K.-J., Piggott A.M., Lacey E., Hancock J.F. and Capon R.J. (2014) Rare Streptomyces sp. polyketides as modulators of K-Ras localisation. Organic and Biomolecular Chemistry, 12 27: 4872-4878.

Raju, Ritesh, Khalil, Zeinab G., Piggott, Andrew M., Blumenthal, Antje, Gardiner, Donald L., Skinner-Adams, Tina S. and Capon, Robert J. (2014) Mollemycin A: an antimalarial and antibacterial glyco-hexadepsipeptide-polyketide from an Australian marine-derived Streptomyces sp. (CMB-M0244). Organic Letters, 16 6: 1716-1719.

Balansa, Walter, Islam, Robiul, Fontaine, Frank, Piggott, Andrew M., Zhang, Hua, Xiao, Xue, Webb, Timothy I., Gilbert, Daniel F., Lynch, Joseph W. and Capon, Robert J. (2013) Sesterterpene glycinyl-lactams: a new class of glycine receptor modulator from Australian marine sponges of the genus Psammocinia. Organic and Biomolecular Chemistry, 11 28: 4695-4701.

Wang, Qian, Song, Fuhang, Xiao, Xue, Huang, Pei, Li, Li, Monte, Aaron, Abdel-Mageed, Wael M., Wang, Jian, Guo, Hui, He, Wenni, Xie, Feng, Dai, Huanqin, Liu, Miaomiao, Chen, Caixia, Xu, Hao, Liu, Mei, Piggott, Andrew M., Liu, Xueting, Capon, Robert J. and Zhang, Lixin (2013) Abyssomicins from the South China Sea deep-sea sediment Verrucosispora sp.: natural thioether michael addition adducts as antitubercular prodrugs. Angewandte Chemie International Edition, 52 4: 1231-1234.

Crossland, Michael R., Haramura, Takashi, Salim, Angela A., Capon, Robert J. and Shine, Richard (2012) Exploiting intraspecific competitive mechanisms to control invasive cane toads (Rhinella marina). Proceedings of the Royal Society B-Biological Sciences, 279 1742: 3436-3442.

Group contacts

Professor Rob Capon
Group leader
+61 7 334 62372
r.capon@imb.uq.edu.au
Mr Venkat Kamalakkannan
Research higher degree student
+61 7 334 62372
v.kamalakkannan@imb.uq.edu.au
 
Mr Pritesh Prasad
Research higher degree student
+61 7 334 62372
p.prasad@imb.uq.edu.au
Mr Pradeep Dewapriya
Research higher degree student
+61 7 334 62372
k.wardamunegedara@uq.edu.au
Ms Michelle Quezada Iniguez
Research higher degree student
+61 7 334 62372
m.quezadainiguez@imb.uq.edu.au
Mr Zhuo (Alex) Shang
Research higher degree student
+61 7 334 62372
z.shang@imb.uq.edu.au
Mr Rakesh Damodar
Research higher degree student
+61 7 334 62372
d.origanti@imb.uq.edu.au
Dr Lea Indjein
Research staff
+61 7 334 62372
+61 7 334 62980
l.indjein@imb.uq.edu.au
Dr Fuhang Song
Visiting Academic
+61 7 334 62372
+61 7 334 62980
f.song@imb.uq.edu.au
Dr Breno Esposito
Visiting Academic
+61 7 334 62372
+61 7 334 62980
breno@iq.usp.br
Mr Pratik Neupane
Research higher degree student
+61 7 334 62372
p.neupane@imb.uq.edu.au
Dr Xue (Sean) Xiao
Research staff
+61 7 334 62372
+61 7 334 62980
xue.xiao@imb.uq.edu.au 
Mrs Pabasara Kalansuriya
Research higher degree student
+61 7 334 62372
p.kalansuriya@imb.uq.edu.au
Mr Ahmad Rosli
Research higher degree student
+61 7 334 62372
a.rosli@imb.uq.edu.au
Dr Xiuli Xu
Visiting Academic
+61 7 334 62372
+61 7 334 62980
x.xu@imb.uq.edu.au
Dr Zeinab Khalil
Research staff
+61 7 334 62372
+61 7 334 62388
z.khalil@imb.uq.edu.au
 Dr Angela Salim
Research staff
+61 7 334 62372
+61 7 334 62980
a.salim@imb.uq.edu.au
Ms Yongmei Zhao
Research higher degree student
+61 7 334 62372
y.zhao@imb.uq.edu.au